Problem with bios and windows 10

Hi. It is possible that the bios I can't install install windows 10? I try install windows 10 on asus x59sl. Always says error xxxxxxxx in safe boot. I try disconnect cd-rom,battery,wifi,drivers graphics card (radeon hd 3470) but it's impossible. I have installed windows 10 on virtual machine and is compatible. What's is bad on the bios?
( Microsoft says that can be the bios ). There are anyway to change and solve it?
Thanks and sorry for my english